No, it doesn't, and either way Garrus isn't going to turn down the opportunity to have a few drinks with a friend.

Albeit a friend who looks a little bit different than the last time he saw her.

"Shepard," He greets her at the door before pausing briefly, noticing the angry red glow of the scars she'd gotten from Project Lazarus.

"I take it the magic running around this place caught you too?"

Because, amazingly, the first thing that comes to his mind isn't 'My best friend has been replaced by her evil twin'.